Something must be done to wipe out this ghastly menace. This is the first film to fully inform the public of the dangers of habitual marijuana use. Parents are lectured during this cautionary tale on how easy is it for wayward students lured by pushers to fall prey to such tragic events as a hit and run accident, manslaughter, suicide, rape, and a descent into general madness.
The tale revolves around Mae and Jack, accomplices in the distribution of marijuana, who manage to entice local high school kids to stop by Mae's apartment to smoke reefer, where stoned ne'er-do-wells laugh fiendishly, dance, and play the piano.
Jack invites the clean-cut couple Bill and Mary, up to his den of sin. After one joint, Bill is hooked, and his life begins to plummet down the tubes. When Mary smokes, she begins giggling uncontrollably while being aggressively fondled by the bizarre addict Ralph. Bill bursts out of the bedroom to tangle with Ralph, prompting a string of calamitous occurrences, including several more deaths and courtroom sentences to mental institutions, all because of the devil weed.