Young Nicholas and his family enjoy a comfortable life, until Nicholas' father dies and the family is left penniless. Nicholas, his sister and mother venture to London to seek help from their Uncle Ralph, but Ralph's only intentions are to separate the family and exploit them. Nicholas is sent to a school run by the cruel, abusive and horridly entertaining Wackford Squeers. Eventually, Nicholas runs away with schoolmate Smike, and the two set off to reunite the Nickleby family.