I imagine that the focus of ancient cultures in this movie will probably be the Mayans, but anyone interested in this should research The Sumerians. And for any of you who read the comment above from the person that goes by the name 'Cool', the Sleeping Prophet's name is Edgar Cayce...And he is the world's most accurate psychic.
My thoughts are that "time" will change. Time is relative. Perhaps, the birth of time travel will be that change, or maybe, time as we know it will really stop...Who the hell knows.
What I do know is on December 21, 2012, we will experience a grand alignment. The winter solstice sun will be in galactic center, and this happens once every 26,000 years. Also, the earth's axis will shift. I know that the Sumerians knew about the galaxy in its entirety 6,000 years ago (including an additional planet), and we've only known about Pluto's existence since 1930. Good luck finding your truth out there, and be careful, because there is a lot of B.S. out there too that will point you nowhere.
The name in which I posted under would be worth researching as well.