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Additional information for Splice, which has a domestic theatrical release set for June 4, 2010. The film is being distributed by Warner Bros Pictures and has not yet been rated. Splice has a total running time of 104 minutes.

  • R USA
  • 15 UK
  • 14A Canada
  • 16 Germany
  • K-15 Finland
  • 15A Ireland
  • 16 Switzerland
  • 18 South Korea
  • 15 Norway
  • -12 France
  • R16 New Zealand
  • MA Australia
  • 18 Malaysia
  • PG-13 Philippines
  • 16 Netherlands
  • III Hong Kong
  • R21 Singapore
  • M/16 Portugal
  • VM14 Italy
  • 16 Spain
  • 16 Argentina
  • 18 Peru
  • 104min
  • Hibrid Croatia
  • Hibrid Hungary
  • Hibrid Romania
  • Splice: Experimento mortal Argentina
  • Splice: Experimento mortal Peru
  • Химера Russia
  • Deney: DNA Turkey
  • Hübriid Estonia
  • Istota Poland
  • Nouvelle espèce Canada
  • Splice Greece
  • Splice - A Nova Espécie Brazil
  • Splice - Das Genexperiment Germany
  • Splice - Mutante Portugal
  • Splice. Experimento mortal Spain
  • Splice: experimento mortal Mexico
  • October 06, 2009 Spain
  • January 22, 2010 USA
  • January 30, 2010 France
  • February 24, 2010 Belgium
  • February 27, 2010 UK
  • March 13, 2010 Germany
  • March 14, 2010 Germany
  • March 20, 2010 Germany
  • March 21, 2010 Germany
  • March 26, 2010 Germany
  • March 27, 2010 Germany
  • March 28, 2010 Germany
  • April 28, 2010 UK
  • May 30, 2010 USA
  • June 03, 2010 Germany
  • June 03, 2010 Switzerland
  • June 04, 2010 Canada
  • June 04, 2010 Estonia
  • June 04, 2010 USA
  • June 13, 2010 Italy
  • June 18, 2010 Poland
  • June 24, 2010 Russia
  • June 30, 2010 France
  • June 30, 2010 Indonesia
  • June 30, 2010 Switzerland
  • July 01, 2010 South Korea
  • July 15, 2010 Kazakhstan
  • July 23, 2010 Australia
  • July 23, 2010 Ireland
  • July 23, 2010 Turkey
  • July 23, 2010 UK
  • July 30, 2010 Finland
  • July 30, 2010 Norway
  • July 30, 2010 Spain
  • August 05, 2010 Kuwait
  • August 12, 2010 Australia
  • August 18, 2010 Philippines
  • August 20, 2010 Romania
  • August 27, 2010 Austria
  • September 16, 2010 Hong Kong
  • September 16, 2010 Netherlands
  • September 18, 2010 Greece
  • September 23, 2010 Hungary
  • September 30, 2010 Greece
  • October 08, 2010 South Africa
  • January 08, 2011 Japan
  • January 14, 2011 Mexico
  • February 04, 2011 Brazil
  • March 03, 2011 Portugal
  • June 09, 2011 Peru
  • July 13, 2011 Argentina
  • No taglines exist for this title.
  • Genetic engineers Clive Nicoli and Elsa Kast hope to achieve fame by successfully splicing together the DNA of different animals to create new hybrid animals for medical use.
  • Genetic engineers Clive Nicoli (Adrien Brody) and Elsa Kast (Sarah Polley) achieve fame by successfully splicing together the DNA of different animals to create incredible new hybrid animals. Now they want to use human DNA in a hybrid that could revolutionize science and medicine. But the pharmaceutical company that funds their research, N.E.R.D. (Nucleic Exchange Research & Development), forbids it, instead mandating that their department be reorganized to focus on finding & extracting certain proteins from the creatures they have already created. Not wishing to spend all their time engaged in what they consider mundane research for the next 5-10 years, Clive and Elsa secretly conduct their own experiments, blending human DNA with that of other animals.Though they disagree about actually bringing the hybrid to term, Elsa pushes the issue and she persuades Clive to go along with it, in continued secrecy. They name their creature Dren (nerd backwards), who exceeds their wildest dreams; she begins to grow and learn at an accelerated rate. As their lab becomes exceedingly crowded, and the risk of Dren being discovered increases, they move Dren to Elsa's late mother's farm.Their work at the company suffers as their attention is focused on Dren. One of the original hybrid animals that they had created, which was originally female, had changed sex unbeknownst to Clive & Elsa since they were distracted. This led to a disastrous presentation during a company shareholders' meeting, when the two original hybrids, previously one male and one female very much in love with each other, became both male, killed each other in front of shareholders and potential investors. Following this meeting, N.E.R.D., found itself in danger of going out of business unless they could find a profitable discovery.Meanwhile, Dren has become amphibious and omnivorous with a toxic sting and retractable wings coming out of parts of her arm and back. Elsa, who had formed a maternal bond with Dren, changes her mind after Dren shows violent behavior, killing her own pet cat out of spite and assaulting her. She cuts off her stinger and uses organic tissue from it to finally isolate and synthesize a protein they had been searching for.Soon after, Clive is seduced by Dren and has sex with her, much to Elsa's disgust; during her sexual encounter with Clive, Dren reveals that she had regenerated her stinger. Elsa and Clive have a heated argument about Clive having cheated, when he confronts her, having figured out that she used samples of her own DNA in the creation of Dren. Deciding to deal with Dren, they go back to the farm, only to discover her body in the water tank, apparently dead.They bury Dren near the farmhouse but before they leave, their boss from pharmaceutical company arrives, having figured out that there was some sort of human hybrid because of the DNA present in the protein they had finally synthesized. Elsa tells her boss he can dig up Dren's body if he really wants to see it. Suddenly, they are attacked by Dren, who was not dead, but apparently in some sort of coma as her body underwent changes that turned her into a male. After killing her boss and Clive's brother, Dren drags Clive into a freezing pond. Elsa pulls him out, but he is unconscious, so Elsa flees. Dren finds her and rapes her. As Dren is raping Elsa, Clive comes to the rescue, impaling Dren with a large sharp branch. Dren kills Clive with a toxic sting, but is dealt a fatal blow by Elsa when she smashes his head with a rock.Later on, Elsa is seen in the office of the pharmaceutical company's head and is given a massive amount of money in exchange for her silence and taking the experiment to the "next stage". The head of the company then thanks Elsa for the personal risk that she is undergoing. Elsa stands up and is revealed to be pregnant with Dren's baby.
  • Vincenzo Natali
    Director(s)
  • Vincenzo Natali
    Antoinette Terry Bryant
    Doug Taylor
    Vincenzo Natali
    Antoinette Terry Bryant
    Writer(s)
  • Joseph Boccia
    line producer
    Yves Chevalier
    executive producer
    Franck Chorot
    executive producer
    Guillermo del Toro
    executive producer
    Sidonie Dumas
    executive producer
    Steven Hoban
    producer
    Susan Montford
    executive producer
    Don Murphy
    executive producer
    Christophe Riandee
    executive producer
    Producer(s)
  • Cyrille Aufort
    Composer(s)
  • Clive Nicoli Adrien Brody
  • Elsa Kast Sarah Polley
  • Dren (as Delphine Chaneac) Delphine Chanéac
  • Gavin Nicoli Brandon McGibbon
  • Joan Chorot Simona Maicanescu
  • William Barlow David Hewlett
  • Child Dren Abigail Chu
  • Paintball Shooter (uncredited) Jonathan Payne
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